PHARMACOLOGY AND PHARMACOTHERAPY

The course in Pharmacology and Pharmacotherapy includes face-to-face lectures and it is aimed to provide students with the pharmacological bases of therapy and the pharmacological profiles of the most commonly used drugs.

At the end of the course the student will be able to:

1) describe the mechanism of action and therapeutic uses of the main drugs prescribed in therapy;

2) describe the pharmacokinetic and pharmacodynamic concepts that regulate the pharmacological profile of the most used drugs.

Face-to-face lectures

GENERAL PHARMACOLOGY

Pharmacokinetics: The Dynamics of Drug Absorption, Distribution, Metabolism, and Elimination

Pharmacodynamics: Molecular Mechanisms of Drug Action

NEUROTRANSMISSION. THE AUTONOMIC AND SOMATIC MOTOR NERVOUS SYSTEMS

Muscarinic Receptor Agonists and Antagonists

Anticholinesterase Agents

Agents Acting at the Neuromuscular Junction and Autonomic Ganglia

Adrenergic Agonists and Antagonists

5-Hydroxytryptamine (Serotonin) and Dopamine

NEUROTANMISSION AND THE CENTRAL NERVOUS SYSTEM

Drug Therapy of Depression and Anxiety Disorders

Pharmacotherapy of Psychosis and Mania

Hypnotics and Sedatives

Opioids, Analgesia, and Pain Management

General Anesthetics and Therapeutic Gases

Local Anesthetics

Pharmacotherapy of the Epilepsies

Treatment of Parkinson Disease

MODULATION OF CARDIOVASCULAR FUNCTION

Regulation of Renal Function and Vascular Volume

The Renin-Angiotensin System

Pharmacotherapy of Hypertension

Pharmacotherapy of Congestive Heart Failure

Anti-Arrhythmic Drugs

Blood Coagulation and Anticoagulant, Fibrinolytic, and Antiplatelet Drugs

Drug Therapy for Hypercholesterolemia and Dyslipidemia

INFLAMMATION AND IMMUNOMODULATION

Histamine, Bradykinin, and Their Antagonists

Anti-Inflammatory, Antipyretic, and Analgesic Agents

Endocrine Pancreas and Pharmacotherapy of Diabetes Mellitus

Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease

GENERAL PRINCIPLES OF ANTIMICROBIAL THERAPY

GENERAL PRINCIPLES OF CANCER CHEMOTHERAPY

1- F. Clementi, G. Fumagalli. Farmacologia Generale e Molecolare. Quarta edizione. UTET

2- F. Rossi, V. Cuomo, C. Riccardi. Farmacologia. principi di base e applicazioni terapeutiche. Seconda edizione. Edizioni Minerva Medica.

3- B. G. Katzung Basic and Clinical Pharmacology. Latest edition.

4- Goodman and Gilman. The Pharmacological Basis of Therapeutics. Latest edition.