CHIMICA ORGANICA - ELEMENTI DI CHIMICA FISICA

Module ELEMENTI DI CHIMICA FISICA

Knowledge and understanding: the student acquires the knowledge of the basic laws of chemistry and physics necessary to understand the origin and evolution of chemical, biochemical and biological phenomena and their applications in the pharmaceutical field.
Ability to apply knowledge and understanding: the student acquires the principles of thermodynamics and how these allow or set limits in the various energy transformations.
Learning skills: the student becomes able to apply chemical-physical models for the rationalization of experiments.

Making judgments: after consolidating the basic concepts, the student develops his critical ability in evaluating and interpreting the data that allow him to independently undertake subsequent research in the chemical-pharmaceutical sector.

Communication skills: The student is able to present knowledge and applications of physical chemistry in both academic and professional contexts, using appropriate technical-scientific language.

Lectures and numerical exercises on the basic concepts and on the many and applications in the chemical-pharmaceutical field.

According to the RDA, Art. 12 - University Training Credits (CFU), the standard load of 25 hours of overall student commitment, corresponding to one credit, can include: a) 7 hours dedicated to lectures or equivalent teaching activities and the remainder to individual study; b) at least 12 and no more than 15 hours dedicated to classroom exercises or equivalent supervised activities (workshops) and the remainder to personal study and reworking.

If lectures are given in a mixed or remote way, some changes may be introduced from what has been stated above, in order to comply with the program and visaged and reported in the syllabus.

Attendance of lessons is required in accordance with the regulation of the CdS as reported in the link: http://www.dsf.unict.it/corsi/l-12_sfa/piani-di-studio.

THERMODYNAMICS

The first law of thermodynamics. Work and Heat. State functions: internal energy, enthalpy, heat capacity at constant pressure and volume. Thermochemistry. Standard enthalpy, enthalpy of reaction, enthalpies of formation, bond energy endothermic and exothermic processes The Hess's law.

The second principle of thermodynamics. Entropy and spontaneous processes. Absolute entropy. Gibbs free energy. Gibbs energy dependence on pressure. Chemical equilibrium. Thermodynamic equilibrium constants. Homogeneous and heterogeneous equilibria. Effect of temperature on equilibrium. 

ELECTROCHEMISTRY

Conductivity of electrolyte solutions, conductometry and conductometric titrations. Electrodic potentials, half-cells, batteries, Nernst equation. Standard reduction potentials and its applications in chemistry and biochemistry. Potentiometry.

CHEMICAL KINETICS

Rates of chemical reactions, reaction order. Integrated form of the kinetic equations of zero, first and second order. Parallel-competitive reactions, consecutive reactions and reactions at the equilibrium. Reaction mechanisms and reaction order. Catalysis.

1. Lecture notes are available.

2. Engel T., Reid P., "Chimica Fisica" PICCIN.

3. G.K. Vemulapalli “Chimica Fisica” Ed. EDISES

3. P.W. Atkins, J. De Paula "Chimica Fisica Biologica" Volume 1, Ed. Zanichelli

5. A Gambi "Esercizi di chimica fisica" Ed. Zanichelli

ASSESSMENT CRITERIA
The final examination will be assessed on the basis of equally weighted indicators, in accordance with the intended learning outcomes (Dublin Descriptors).
The final grade takes into account the following aspects.
Quality of Knowledge, Skills and Competences
·appropriateness, accuracy, and consistency of the knowledge demonstrated;
·appropriateness, accuracy, and consistency of the skills demonstrated;
·appropriateness, accuracy, and consistency of the competences demonstrated.
Communication Skills
·clarity and effectiveness of presentation;
·appropriate use of discipline-specific terminology;
·logical reasoning and coherence in the organization of the contents;
·ability to establish connections among different topics by identifying common elements and developing a coherent overall framework, with appropriate structure, organization, and logical progression;
·ability to summarize concepts effectively, including the use of discipline-specific symbols and graphical representations, such as formulas, diagrams, and equations.
Interpersonal Skills
·willingness to engage in discussion and interact with the examiner during the oral examination.
Personal Skills
·critical thinking;
·self-assessment skills;
·problem-solving skills;
·decision-making skills.
 
The average duration of the oral examination is approximately 40 minutes.
 
The final grade is expressed on a 30-point scale according to the following criteria.
Fail (Not Passed)
Knowledge and understanding: significant gaps and inaccuracies.
Analytical and synthesis skills: inadequate, with frequent generalizations.
Use of references: completely inappropriate.
Grade: 18–20
Knowledge and understanding: very limited, with evident shortcomings.
Analytical and synthesis skills: barely satisfactory.
Use of references: barely appropriate.
Grade: 21–23
Knowledge and understanding: slightly above the minimum acceptable level.
Analytical and synthesis skills: satisfactory analytical and synthesis abilities; arguments are presented logically and coherently.
Use of references: appropriate use of standard references.
Grade: 24–26
Knowledge and understanding: good.
Analytical and synthesis skills: good analytical and synthesis abilities; topics are presented clearly and coherently.
Use of references: appropriate use of standard references.
Grade: 27–29
Knowledge and understanding: very good.
Analytical and synthesis skills: strong analytical and synthesis abilities.
Use of references: demonstrates in-depth study of the subject.
Grade: 30–30 cum laude
Knowledge and understanding: excellent.
Analytical and synthesis skills: outstanding analytical and synthesis abilities.
Use of references: demonstrates extensive and critical in-depth knowledge of the subject.
 
Information for Students with Disabilities and/or Specific Learning Disorders (SLD)
To ensure equal opportunities and in compliance with current legislation, students with disabilities and/or specific learning disorders (SLD) may request an individual meeting to discuss and arrange appropriate compensatory and/or dispensatory measures according to the course learning objectives and their specific needs. Students may contact Prof. Santina Chiechio (santina.chiechio@unict.it), who also serves as the Departmental CInAP Representative (Centre for Active and Participatory Inclusion – Services for Students with Disabilities and/or Specific Learning Disorders) of the Department of Drug and Health Sciences.
 
Examination Dates
Examination dates are published on the website of the Department of Drug and Health Sciences. https://www.dsf.unict.it/it/corsi/l-29_sfa/calendario-esami
 
ECTS Workload
According to the University Academic Regulations (RDA), Article 12 – University Educational Credits (CFU/ECTS), one credit corresponds to a standard workload of 25 hours of total student commitment, including: 7 hours of lectures or equivalent teaching activities, with the remaining time devoted to independent study; or 12 to 15 hours of classroom exercises or equivalent supervised activities (e.g., laboratory work), with the remaining time devoted to individual study and personal elaboration.

Reaction rate, specific rate constant, and reaction order.

Kinetic models of consecutive and competing reactions and their applications in the study of ecosystems.

The second law of thermodynamics and issues related to environmental pollution.

Schematize an experimental apparatus for realizing a battery with unitary activity chemical species by indicating the polarity in flow of the electrons in the external circuit and the flow of the charges of the salt bridge.

Determination of chemical species via electrochemical measurements: potentiometry and conductometry.