BIOLOGIA FARMACEUTICA G - O

Knowledge and understanding: The course provides the tools to describe the structures and the main cellular biological processes using appropriate scientific terminology;

Ability to apply knowledge and understanding: the student acquires the skills necessary to distinguish and motivate the difference between living organisms;

Learning skills: the student becomes able to use the knowledge on the basic mechanisms that regulate cellular life and living organisms (animals and plants) as a substrate for the study of other biological subjects of the Degree Course;

Autonomy of judgment: the student develops his critical ability to evaluate the implications and results of innovative discoveries in the field of cell biology and living organisms by consulting the most recent scientific literature.

Face-to face-lesson (42 hours).Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.
 

Information for students with disabilities and/or SLD:

To guarantee equal opportunities and in compliance with the laws in force, interested students can request a personal interview in order to plan any compensatory and / or dispensative measures, based on educational objectives and specific needs. It is also possible to contact the CInAP referent teacher (Center for Active and Participatory Integration - Services for Disabilities and / or DSA) of our Department, Prof. Teresa Musumeci.

Composition and organization of living matter.

Chemical composition of the cell: water, minerals, amino acids, proteins, lipids, carbohydrates, nucleic acids.

Principles of classification of living organisms: prokaryotes and eukaryotes and the relationship with the ecosystem.

Morphology of animal and vegetable cells.

Cell wall, growth of the cell wall. Changes in the cell wall: lignification, mineralization, gelation, pigmentation.

Structure and function of the plasma membrane: cell permeability, transport, exocytosis and endocytosis.

Intracellular structures: Nucleus, Endoplasmic Reticulum, Ribosomes, Golgi Complex, Lysosome, Vacuoles   (microbodies), Mitochondria, Cytoskeleton, Chloroplasts, chromoplasts, leucoplasts.

Biochemical mechanism of photosynthetic light reactions, photorespiration.

Metabolism: primary metabolites, intermediate metabolites and secondary metabolites.

Cell cycle. DNA replication, mitosis, meiosis, mutations in the DNA.

Overview of genetics: concepts of heterozygous, homozygous and hemizygous, dominant and recessive characters, genotype, phenotype and karyotype, Mendel's laws.

Genetic code, transcription, translation.

The program is divided into three parts based on a temporal sequence of the topics covered.

PART ONE 2.5 CFU – 17.5 h

Living matter composition. Water and mineral salts, amino acids and proteins, carbohydrates and lipids, nucleic acids, living organisms, prokaryotes, eukaryotes and their relationship.Difference between eukaryotic cell and prokaryotic cell, Structure and transport of the biological membrane. Organelles: Reticuloendoplasmic; Golgi apparatus, Mitochondria; Lysosomes, Peroxisomes; Ribosomes, Cytoskeleton; Nucleus, Chromatin and Chromosomes

SECOND PART 2 CFU – 14 h

Difference between plant cell and animal cell: Plastids. Notes on Photosynthesis; Photorespiration; C3 plants and C4 plants; Vacuoles; Secondary metabolites; Cell wall. Cell wall growth. Cell wall modifications: lignification, cutinization, suberification, mineralization, gelation, pigmentation

THIRD PART 1.5 CFU - 10.5 h

Notes on genetics: concepts of heterozygote, homozygote and hemizygote, dominance and recessivity of traits, genotype, phenotype and karyotype, Mendel's laws. Congenital Defects. Cellular Cycle; DNA synthesis, Mitosis; Meiosis, RNA Transcription; Notes on protein synthesis.

1. Solomon, Martin, Martin, Berg -Biologia-   Ed. Edises

2. Solomon, Martin, Martin, Berg -Elementi Biologia-  Ed. Edises integrated with

3. Solomon, Martin, Martin, Berg -Evoluzione e Biodiversità-  Ed. Edises and with

4. Solomon,  Martin, Martin, Berg-Struttura e processi vitali nelle piante- V Ed. Edises

5.Hardin, Bertoni- Becker. Il mondo della cellula- , Ed. Pearson

6.Sadava,Hillis, Craig Heller, Hacker.Biologia , Volumi 1,2,3,4 Ed. Zanichelli

7.  Poli F. - Biologia Farmaceutica - II Ed. - Pearson 2019

8. Chessa M, Maggi F, Menghini L, Nicoletti M. Biologia farmaceutica-Ed. EDISES

1. Function and structure of cellulose

2, Difference between prokaryotic and eukaryotic cell

3. Membrane transport

4. DNA replication