MICROBIOLOGY

Get to know the bacterial cell structures in depth.

Know the main fungi related to infections, to toxins, to poisonings, and to environmental contamination.

To know viral and sub-viral structures and their applications in the field of biomedicine

To know basis of microbial genetics, cell growth, differentiation and other microbial vital forms.

Know the parasitic host relationships both from the point of view of medical microbiology, know the main microbial species of medical interest and the therapeutic modalities,
know the basis ofmicrobial cultivation techniques, infection control techniques, and general notions about infectious disease prevention

Lectures. Should the circumstances require online or blended teaching, appropriate modifications to what is hereby stated may be introduced, in order to achieve the main objectives of the course

Information for students with disabilities and / or SLD: To guarantee equal opportunities and in compliance with the laws in force, interested students can ask for a personal interview in order to plan any compensatory and / or dispensatory measures, based on the teaching objectives and specifications needs. It is also possible to contact the CInAP contact person (Center for Active and Participatory Integration - Services for Disabilities and / or SLD) of the department.

1. The prokaryotic cell, fungi and virus
   1. The organization of the bacterial cell
   2. The capsule and other external structures
   3. The outer membrane and peptidoglycan
   4. The cytoplasmic membrane
   5. The Pili and other types of bacterial appendices
   6. Flagella and bacterial movement
   7. The cytoplasmic organelles
   8. The membrane transport and secretion systems
   9. Bacterial nucleoid
   10. The fungal cell
   11. General features of fungi
   12. The organization of viral particle and Viral simmetry
   13. Replicative classes
       
   14. Viroids, Virusoid and Prions
       
   15. The bacteriophage
       
2. Microbial genetics - Cell growth and differentiation
   1. The concept of transferring genetic information in prokaryotes; Recombination from prokaryotes to eukaryotes; Plasmids and trasposons; The cell cycle and  bacterial division; Vital not cultivable status and  microbial biofilms; The spore
   2. Fungal life cycle
3. Host parasite relationships
   1. Bacterial infection
   2. Viral infection
   3. Fungal infection and its classification
   4. The host response to infection
4. Diversity and systematics of the microbial worl, cultivation, prevention and therapy
   1. Special Bacteriology (main features, diseases, chemotherapy and prevention opportunities)
      • The main features of: Staphylococcus, Streptococcus, Enterococcus, Neisseria, Branhamella, Mycobacterium, Streptomyces, Nocardia, Actinomyces, Corynebacterium, Lactobacillus, Bartonella, Listeria, Gardnerella, Bacillus, Clostridium, Enterobacteriaceae, Haemophilus, Pasteurella, Vibrio, Legionella, Brucella, Bordetella, Acinetobacter, Pseudomonas, Bacteroides, Campylobacter, Helicobacter, Mycoplasma, Ureaplasma, Chlamydiaceae, Rickettsiaceae, Spirochetaceae.
   2. Special virology (main features, diseases, chemotherapy and prevention opportunities)
      • The main features of: Poxviridae, Herpesviridae, Adenoviridae, Papillomavirus e Polyomavirus umani,Parvoviridae, Paramyxoviridae, Orthomyxoviridae, Picornaviridae, Arenaviridae, Bunyaviridae, Caliciviridae, Coronaviridae, Filoviridae, Flaviridae, Reoviridae, retrovirus umani, Togaviridae e Rubivirus,  virus delle epatiti (HAV, HBV, HCV, HDV,HEV, HGV)
   3. Special mycology (main features, diseases, chemotherapy and prevention opportunities)
      • Yeasts: Candida, Cryptoococcus, Malassezia, Pnuemocystis
      • Moulds: Dermatophytes,  Aspergillus
      • Dimorphic fungi: Blastomyces, Coccidioides, Paracoccidioides, Histoplasma, Sporothrix, Talaromyces
5. Infection control. The microbial cultivation techniques. General notions on the prevention of infectious diseases;
   1. Sterilization and disinfection techniques
      • Sterilization by physical methods
      • Sterilization by  chemical methods
   2. Preparation of land in the microbiology laboratory
   3. The cultivation of microorganisms: viruses, prokaryotes and eukaryotes
   4. Procedures for the conservation of microorganisms
   5. Sterilization of work environments
   6. Disinfectants
   7. Biosafety
   8. The main antibiotics: mechanism of action and resistance
   9. The main antifungals: mechanism of action and resistance
   10. The main antivirals: mechanism of action and resistance
   11. The vaccines

Carlone, Pompei, Tullio, Microbiologia Farmaceutica III Edizione, Edises

Microbiology - https://courses.lumenlearning.com/microbiology/

Further resources:

Topley & Wilsons'  su: https://onlinelibrary.wiley.com/doi/book/10.1002/9780470688 (the link must be used within University of Catania network)