Organic Chemistry I

The course aims to provide a critical and scientific mentality and rational use of mnemonic abilities, favoring the ability to apply theoretical knowledge to problem-solving.

This means overcoming the limit of mere "mnemonic repetition" of concepts that, in doing so, would be aimed at simple learning. Critical and scientific mentality at the same time constitute a high-level objective; it requires a synthesis between mental operation and actual realization: the first is expressed in the design of an experiment, in the rational-intuitive control of the execution and calculation phases and the evaluation phase of the results; the second is expressed in the actual execution of the experiment, even at the virtual level.

Therefore, at the end of the course, the student must be able to:

D1 KNOWLEDGE AND UNDERSTANDING ABILITY

D2 ABILITY TO APPLY KNOWLEDGE AND UNDERSTANDING

D3 AUTONOMY OF JUDGMENT

D4 COMMUNICATION SKILLS

D5 LEARNING SKILLS

The course activities consist of lectures and classroom exercises. To these will be added some "case studies" concerning molecules of chemical-pharmaceutical interest. The student is required to actively participate in the discussion of the topics presented and in particular, in the case studies.

Should teaching be carried out in mixed mode or remotely, it may be necessary to introduce changes with respect to previous statements, in line with the programme planned and outlined in the syllabus.

Learning assessment may also be carried out on line, should the conditions require it.

Knowledge of the basic concepts of Mathematics, Physics, and General Chemistry.

Obligatory attendance according to the rules of the teaching regulations of the CdS in CTF as reported in the following link.

Exercises of:

• Nomenclature, acidity and basicity of organic compounds. 
• Stereochemistry.
  
• Reactions of alkanes, alkenes and alkynes.
  
• Sn1, Sn2, E1, E2 reactions.
  
• Reactions of: alcohols, ethers, amines, epoxides, aldehydes, ketones, enolate ions, carboxylic acids and derivatives. 
• Organo-metallic reagents.
  
• Electrophilic and nucleophilic aromatic substitution. Synthesis strategy of polysubstituted aromatic compounds.
• Heterocyclic compounds.

To pass the course, the student will have to take a structured written test and an oral test; the oral exam is accessed by scoring a minimum of 18 out of 30 points in the written exam.

The written test, lasting 90 minutes, consists of 30 multiple choice questions (5 possible answers of which only one is correct), found from the Exam Manager online platform, which will cover the entire program. One point will be attributed to each correct answer while a quarter point will be deducted for each wrong answer (−0.25); the answers not given will be worth zero points. The written test will be passed with a minimum grade of 18/30.

During the examination, it is not allowed to consult books, notes, or electronic devices of any kind.

The oral exam consists of a discussion, lasting about 20-30 minutes, aimed at ascertaining the level of knowledge and understanding reached by the student on the theoretical and methodological contents indicated in the program. The oral exam will also allow you to verify the student's communication skills with properties of language and autonomous organization of the exposition on the same theoretical topics.

Passing the exam with minimum marks requires sufficient knowledge of the topics covered in the various parts of the program. To achieve a score of 30/30 cum laude, the student must demonstrate that he has acquired an excellent knowledge of all the topics covered during the course and that he is able to connect them in a logical and coherent way.

Verification of learning can also be carried out electronically, should the conditions require it.

An example of structured verification is available at the following link.