Rosaria ACQUAVIVA

2015-2020

1. Antibacterial, antioxidant, and hypoglycaemic effects of Thymus capitatus (L.) Hoffmanns. et Link leaves fractions
Iauk L., Acquaviva R., Mastrojeni S., Amodeo A., Pugliese M., Ragusa M., Loizzo M.R., Menichini F., Tundis R.,
Journal of Enzyme Inhibition and Medicinal Chemistry 30, 360-365, 2015. doi: 10.3109/14756366.2014.930453. 

2. Neuroprotective effects of a glutathione depletor in rat post-ischemic reperfusion brain damage.
Di Giacomo C., Santangelo R., Sorrenti V., Li Volti G., Acquaviva R.
CNS Neurol Disord Drug Targets. 14, 41-48, 2015

3. Effects of Tithonia diversifolia (Hemsl.) A. Gray extract on adipocyte differentiation of human mesenchymal stem cells.
Di Giacomo C., Vanella L., Sorrenti V., Santangelo R., Barbagallo I., Calabrese G., Genovese C., Mastrojeni S., Ragusa S., Acquaviva R.
PLoS One. 10(4):e0122320. doi: 10.1371/journal.pone.0122320, 2015
                        
4. Cyanidin induces apoptosis and differentiation in prostate cancer cells.
Sorrenti V., Vanella L., Acquaviva R., Cardile V., Giofrè S., Di Giacomo C.
Int J Oncol. 47, 1303-1310, 2015 doi: 10.3892/ijo.2015.3130. 

5. Caffeic Acid Phenylethyl Ester (Cape) Regulates PPAR’s Levels  In Stem Cells-Derived Adipocytes
Vanella L., Tibullo D., Godos J., Pluchinotta F.R., Di Giacomo C., Sorrenti V., Acquaviva R., Russo A., Li Volti G., Barbagallo I.
PPAR Research. 2016, 2016; doi: 10.1155/2016/7359521. 

6. Effects of extract of Celtis aetnensis (Tornab.) Strobl twigs in human colon cancer cell cultures 
Acquaviva R., Sorrenti V., Santangelo R., Cardile V., Tomasello B., Malfa G., Vanella L., Amodeo A., Mastrojeni S., Pugliese M., Ragusa M., Di Giacomo C.
Oncology Reports 36, 2298-2304, 2016

7. Moringa oleifera Lam. improves lipid metabolism during adipogenic differentiation of human stem cells.
Barbagallo I., Vanella L., Distefano A., Nicolosi D., Maravigna A., Lazzarino G., Di Rosa M., Tibullo D., Acquaviva R., Li Volti G.
Eur Rev Med Pharmacol Sci. 20, 5223-5232, 2016

8. Caffeic Acid Phenethyl Ester restores adipocyte gene profile expression following lipolysaccharide treatment.
Barbagallo I, Li Volti G, Sorrenti V, Di Giacomo C, Acquaviva R, Raffaele M, Galvano F, Vanella L. 
Letters In Drug Design & Discovery 14, 481-487, 2017 

9.  Preliminary study for small animal preclinical hadrontherapy facility
Russo G., Pisciotta, P., Cirrone G.A.P., Romano F., Cammarata F., Marchese V.,
Forte G.I., Lamia D., Minafra L., Bravatá V., Acquaviva R., Gilardia M.C., Cuttone G.
Nuclear Instruments and Methods in Physics Research A 846: 126–134, 2017

10. Novel Caffeic Acid Phenethyl Ester (Cape) Analogues as Inducers of Heme Oxygenase-1.
Pittalà V., Vanella L., Salerno L., Di Giacomo C., Acquaviva R., Raffaele M., Romeo G., Modica M.N., Prezzavento O., Sorrenti V.
Curr Pharm Des. 23, 18, 2657-2664, 2017 

11. Polyphenolic profile and antioxidant activity of olive mill wastewater from two Sicilian olive cultivars: Cerasuola and Nocellara etnea
Di Mauro M.D., Giardina R.C., Fava G., Mirabella E.F., Acquaviva R., Renis M., D’Antona N.
Eur Food Res Technol 243, 1895-1903, 2017 

12. Anti-inflammatory and antioxidant agents from Salvia genus (Lamiaceae): an assessment of the current state of knowledge.
Bonesi M., Loizzo M.R., Acquaviva R., Malfa G.A., Aiello F., Tundis R.
Antiinflamm Antiallergy Agents Med Chem. 16, 70-86, 2017 doi: 10.2174/1871523016666170502121419.

13.  Dietary Compounds, Epigenetic Modifications and Metabolic Diseases
Sorrenti V., Acquaviva R., Cosenza J. and Di Giacomo C.
Current Chemical Biology, 11, 110-126, 2017.

14. Biological activities of Teucrium flavum L., Teucrium fruticans L., and Teucrium siculum Rafin. crude extracts
Acquaviva R., Genovese C., Amodeo A., Tomasello B., Malfa G., Sorrenti V., Tempera G., Addamo A.P., Ragusa S., Tundis R., Menichini F., and Di Giacomo C.
Planta Biosystems 152, 720-727, 2018 

15. Phenolic profile and biological properties of the leaves of Ficus vasta Forssk. (Moraceae) growing in Egypt.
Taviano MF, Rashed K, Filocamo A, Cacciola F, Dugo P, Mondello L, Bisignano C, Acquaviva R, D'Arrigo M, Miceli N.
BMC Complement Altern Med. 2018, 18, 161, 2018. doi: 10.1186/s12906-018-   2210

16. Therapeutic potential of caffeic acid phenethyl ester (CAPE) in diabetes
Pittalà, V., Salerno, L., Romeo, G., Acquaviva R., Di Giacomo, C., Sorrenti, V.
Current Medicinal Chemistry 2018, 25, 4827-4836, 2018

17. In vitro evaluation of biological activities of Orobanche crenata Forssk. leaves extract
Genovese C., Acquaviva R., Ronsisvalle S., Tempera, G., Malfa G.A.,  D’Angeli F., Ragusa S.,  Nicolosi D.
Natural Product Research. 2019, 23, 1-5 doi: 10.1080/14786419.2018.1552697.

18. Antioxidant activities of Solanum nigrum L. leaf extracts determined in in vitro cellular models
Campisi A., Acquaviva R., Raciti G., Duro A., Rizzo M., Santagati N.A.
Foods 2019, 8(2), E63; doi.org/10.3390/foods8020063

19. Blond and blood juice supplementation in high fat diet fed mice: effect on antioxidant status and DDAH/ADMA pathway
Sorrenti V., Di Giacomo C., Acquaviva R., Cosenza J., Carota G. and Galvano F.
RSC Adv., 2019, 9, 11406-11412

20. Protective effects of caffeic acid phenethyl ester (CAPE) and novel CAPE analogue as inducers of Heme Oxygenase-1 in streptozotocin-induced type 1 diabetic rats.
Sorrenti V., Raffaele M., Vanella L., Acquaviva R., Salerno L., Pittalà V., Intagliata S., Di Giacomo C.
Int. J. Mol. Sci. 2019, 20, pii: 2441; doi:10.3390/ijms20102441

21. Betula etnensis Raf. (Betulaceae) extract induced HO-1 expression and ferroptosis cell death in human colon cancer cells
Malfa G.A., Tomasello B., Acquaviva R., Genovese C., La Mantia A., Cammarata F.P., Ragusa M. Renis M., Di Giacomo C.
Int. J. Mol. Sci. 2019, 20, pii2723; doi:10.3390/ijms20112723

22. Antibacterial and anti-biofilm activities of walnut pellicle extract (Juglans regia L.) against coagulase-negative staphylococci
Acquaviva R., D’Angeli F., Malfa G.A., Ronsisvalle S., Garozzo A., Stivala A., Ragusa S., Nicolosi D., Salmeri M., Genovese C.
Natural Product Research 2019, 9, 1-6. doi: 10.1080/14786419.2019.1650352.

23. Anti-adipogenic and anti-oxidant effects of a standardized extract of Moro blood oranges (Citrus sinensis (L.) Osbeck) during adipocyte differentiation of 3T3-L1 preadipocytes  
Tomasello B., Malfa G.A., La Mantia A., Miceli N., Sferrazzo G. Taviano M.F., Di Giacomo C., Renis M., Acquaviva R. 
Natural Product Research  2019, 10.1080/14786419.1660337

24. Contribution of Flavonoids and Iridoids to the Hypoglycaemic, Antioxidant, and Nitric Oxide (NO) Inhibitory Activities of Arbutus unedo L.
Tenuta M.C., Deguin B., Loizzo M.R., Dugay A., Acquaviva R., Malfa G.A., Bonesi M., Bouzidi C. and Tundis R.
Antioxidants 2020, Feb 22;9(2). pii: E184, doi: 10.3390/antiox9020184

25. Brassica incana Ten. (Brassicaceae): phenolic constituents, antioxidant and cytotoxic properties of the leaf and flowering top extracts
Miceli N., Cavò E., Ragusa M., Cacciola F., Mondello L., Dugo L., Acquaviva R., Malfa G.A., Marino A., D’Arrigo M., Taviano M.F.
Molecules 2020, 25 (6), 1461; doi:10.3390/

26. LC-ESI-QTOF-MS profiling, protective effects on oxidative damage, and in-hibitory activity of enzymes linked to type 2 diabetes and nitric oxide production of Vaccinium corymbosum L. (Ericaceae) extracts
Tenuta M.C., Bonesi M., Malfa G.A, Loizzo M.R., Dugay A., Bouzidi C., Acquaviva R., Tundis R., and Deguin B.
Journal of Berry Research 2020    

Libri
1) Cellule staminali: un cerino accesso in una stanza al buio
Acquaviva R. and Vanella L. Spazio libri-editore; 2007, pp.1-23

2) Nitric oxide and skin: effect of natural compounds
A. Russo, R. Acquaviva and L. Vanella
Recent research Developments in Chemistry and Biology of nitric oxide, 2008, pag. 149-179. Ed. Editors: V. Sorrenti, A. Vanella, C. Di Giacomo. Publisher: Transworld Research Network, Kerala, India.

3) Carotenoids as tools in breast cancer therapy
Loizzo M.R., Malfa G., Acquaviva R., Tundis R., Bonesi M.. Carotenoids as tools in breast cancer therapy. Goutam Brahmachari. Vol. 5: Discovery and Development of Anti-Breast Cancerous Agents from Natural Products. Elsevier Series ‘Natural Products Drug Discovery. 2018

4) Prevention and therapy of prostate cancer: the role of triterpene saponins
Bonesi M., Tundis R., Malfa G., Acquaviva R., Loizzo M.R. Prevention and therapy of prostate cancer: the role of triterpene saponins. Goutam Brahmachari. Vol. 7: Discovery and Development of Anti-Prostate Cancerous Agents from Natural Products. Elsevier Series ‘Natural Products Drug Discovery. 2018

5) Handbook of Dietary Phytochemicals
Chapter 5 - Citrus flavanones
Tundis R., Acquaviva R., Bonesi M., Malfa G.A., Tomasello B., Loizzo M.R in press

Catania 29 Novembre 2020

- Tossicità dell'ossigeno e sistemi scavengers delle forme parzialmente ridotte dell'ossigeno in diversi sistemi biologici e condizioni fisio-patologiche;

- Apoptosi e proteine da stress;

- Prevenzione dei danni da ischemia e riperfusione epatica, cerebrale e renale;

- Attività biologiche di Piante medicinali ed edibili;

- Studio di sostanze naturali ad attività antiossidante e loro utilizzo terapeutico;

- Caratterizzazione dell’attività biologica e dei meccanismi di azione di estratti vegetali e di sostanze naturali;

- Caratterizzazione dell'attività biologica e dei meccanismi d'azione di estratti in linee tumorali ed in patologie dismetaboliche.

Catania 29 Novembre 2020