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Prodotti della Ricerca / Research products

Elenco delle Pubblicazioni scientifiche recenti / Recent scientifc publications

 

  • Development of a synbiotic formulation based on germinated brown rice and probiotics suitable to support women's well-being. Bosco G, Consoli V, Pino A, Vaccalluzzo A, Caggia C, Sorrenti V, Randazzo C. Food Bioscience DOI: 10.1016/j.fbio.2025.108006.
  • Design of Polycation-Functionalized Resveratrol Nanocrystals for Intranasal Administration. Bonaccorso A, Zingale E, Caruso G, Privitera A, Carbone C, Lo Faro MJ, Caraci F, Musumeci T, Pignatello R. Pharmaceutics. 2025 Oct 18;17(10):1346. doi: 10.3390/pharmaceutics17101346.
  • Origanum majorana Extracts: A Preliminary Comparative Study on Phytochemical Profiles and Bioactive Properties of Valuable Fraction and By-Product. Bianchi S, Acquaviva R, Di Giacomo C, Siracusa L, Issop-Merlen L, Motterlini R, Foresti R, Condorelli D, Malfa GA. Plants (Basel). 2025 Jul 23;14(15):2264. doi: 10.3390/plants14152264.
  • Wild Species from the Asteraceae Family, Traditionally Consumed in Some Mediterranean Countries. Kozuharova E, Malfa GA, Acquaviva R, Valdés B, Batovska D, Stoycheva C, Rejdali M, Marino P, Spadaro V. Plants (Basel). 2025 Jun 30;14(13):2006. doi: 10.3390/plants14132006.
  • Prospective Approaches to the Sustainable Use of Peonies in Bulgaria. Stoycheva C, Batovska D, Malfa GA, Acquaviva R, Statti G, Kozuharova E. Plants (Basel). 2025 Mar 19;14(6):969. doi: 10.3390/plants14060969.
  • Oxalis pes-caprae L. (Oxalidaceae): From Invasive Concern to Promising Bioresource for Health and Sustainable Applications. Malfa GA, Bianchi S, Spadaro V, Di Giacomo C, Raimondo FM, Acquaviva R. Plants (Basel). 2025 Feb 14;14(4):578. doi: 10.3390/plants14040578.
  • Protective Role and Enhanced Intracellular Uptake of Curcumin in Retinal Cells Using Self-Emulsifying Drug Delivery Systems (SNEDDS). Zingale E, Masuzzo S, Lajunen T, Reinisalo M, Rautio J, Consoli V, D'Amico AG, Vanella L, Pignatello R. Pharmaceuticals (Basel). 2025 Feb 17;18(2):265. doi: 10.3390/ph18020265.
  • Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer. Consoli V, Sorrenti V, Gulisano M, Spampinato M, Vanella L. Mol Cell Biochem. 2025 Mar;480(3):1495-1518. doi: 10.1007/s11010-024-05119-5.
  • Mediterranean Food By-products as a Valuable Source of Bioactive Compounds with Health Properties. Santonocito D, Montenegro L, Puglia C. Curr Med Chem. 2025;32(21):4154-4175. doi:10.2174/0109298673309549240723054831.
  • Green techniques to develop food-grade resveratrol Eudraguard® Biotic/Control microparticles as a shield against stress conditions. Lombardo R., Rizzo S., Rautio J., Pignatello R. J. Drug Delivery Sci. Technol., 112, 107286 (2025) doi: 10.1016/j.jddst.2025.107286.
  • Effects of Pterostilbene on the Cell Division Cycle of a Neuroblastoma Cell Line. Bruno F, Naselli F, Brancato D, Volpes S, Cardinale P, Saccone S, Federico C and Caradonna F. Nutrients 2024 November,16,4152. doi: 10.3390/nu16234152.
  • Protective Effects of Wild Sulla coronaria (Fabaceae) Flowers Phytocomplex in Human Dermal Fibroblasts Stimulated with Interleukin-1β. Malfa GA, Bianchi S, Spadaro V, Kozuharova E, Marino P, Pappalardo F, Di Giacomo C, Acquaviva R. Plants (Basel). 2024 Sep 30;13(19):2748. doi: 10.3390/plants13192748.
  • Navigating heme pathways: the breach of heme oxygenase and hemin in breast cancer. Consoli V, Sorrenti V, Gulisano M, Spampinato M, Vanella L. Mol Cell Biochem. 2024 Sep 17. doi: 10.1007/s11010-024-05119-5.
  • Wild Species from the Family Apiaceae, Traditionally Used as Food in Some Mediterranean Countries. Kozuharova E, Malfa GA, Acquaviva R, Valdes B, Aleksanyan A, Batovska D, Stoycheva C, Rejdali M, Al-Tawaha AR, Marino P, Spadaro V. Plants (Basel). 2024 Aug 21;13(16):2324. doi: 10.3390/plants13162324.
  • Effect of Ferulic Acid Loaded in Nanoparticle on Tissue Transglutaminase Expression Levels in Human Glioblastoma Cell Line. Dell'Albani P, Carbone C, Sposito G, Spatuzza M, Chiacchio MA, Grasso R, Legnani L, Santonocito D, Puglia C, Parenti R, Puglisi G, Campisi A. Int J Mol Sci. 2024 Aug 1;25(15):8397. doi: 10.3390/ijms25158397.
  • Mediterranean Food By-products as a Valuable Source of Bioactive Compounds with Health Properties. Santonocito D, Montenegro L, Puglia C. Curr Med Chem. 2024 Jul 25. doi: 10.2174/0109298673309549240723054831.
  • Red Oranges and Olive Leaf Waste-Derived Bioactive Extracts Promote Adipocyte Functionality In Vitro. Gulisano M, Consoli V, Sorrenti V, Vanella L. Nutrients. 2024 Jun 19;16(12):1959. doi: 10.3390/nu16121959.
  • Utility potential of the aggressive invasive Solanum elaeagnifolium Cav. (Solanaceae) as an option to control its expansion: bioactive compounds and medicinal properties. Kozuharova E, Malfa GA, Aquaviva R, Zarev Y, Ionkova Iliana. 2024 May, EURO-MEDITERRANEAN JOURNAL FOR ENVIRONMENTAL INTEGRATION DOI10.1007/s41207-024-00533-z.
  • Synthesis and in Vitro Evaluation of CAPE Derivatives as Ferroptosis Inducers in Triple Negative Breast Cancer. Consoli V, Fallica AN, Virzì NF, Salerno L, Intagliata S, Sorrenti V, Greish K, Giuffrida A, Vanella L, Pittalà V. ACS Med Chem Lett. 2024 Apr 30;15(5):706-713. doi: 10.1021/acsmedchemlett.4c00099.
  • Innovative snail-mucus-extract (SME)-coated nanoparticles exhibit anti-inflammatory and anti-proliferative effects for potential skin cancer prevention and treatment. Consoli V, Petralia S, Vanella L, Gulisano M, Maugeri L, Satriano C, Montenegro L, Castellano A, Sorrenti V. RSC Adv. 2024 May 1;14(20):14357. doi: 10.1039/d4ra90049a.
  • 1,4-dihydroxy quininib activates ferroptosis pathways in metastatic uveal melanoma and reveals a novel prognostic biomarker signature. Tonelotto V, Costa-Garcia M, O'Reilly E, Smith KF, Slater K, Dillon ET, Pendino M, Higgins C, Sist P, Bosch R, Passamonti S, Piulats JM, Villanueva A, Tramer F, Vanella L, Carey M, Kennedy BN. Cell Death Discov. 2024 Feb 10;10(1):70. doi: 10.1038/s41420-023-01773-8.
  • Redox State Modulatory Activity and Cytotoxicity of Olea Europaea L. (Oleaceae) Leaves Extract Enriched in Polyphenols Using Macroporous Resin. Luca T, Malfa GA, Siracusa L, La Mantia A, Bianchi S, Napoli E, Puleo S, Sergi A, Acquaviva R, Castorina S. Antioxidants (Basel). 2024 Jan 4;13(1):73. doi: 10.3390/antiox13010073.
  • Emulsifying salts and P2O5 content as promising strategies to control Bacillus cereus growth during storage of processed cheese. Fusieger A, Russo N, Nero L, De Carvalho AF, Randazzo C, Caggia C. International Journal Of Dairy Technology. 2024 Feb, Vol 77 Issue 1, 198-211 doi: 10.1111/1471-0307.13023.
  • Effect of microbial fermentation on functional traits and volatiloma profile of pâté olive cake. Foti P, Randazzo CL, Russo M, Di Sanzo R, Romeo FV, Scilimati A, Miciaccia M, Grazia Perrone M, Caggia C. Food Res Int. 2023 Dec;174(Pt 1):113510. doi: 10.1016/j.foodres.2023.113510.
  • A Potentially Alternative Route to Predict Crystal Morphologies of Indicaxanthin Crystals. Lombardo GM, Grassi A, Punzo F. Pharmaceutical Chemistry Journal. 2023
  • Current challenges of microalgae applications: exploiting the potential of non-conventional microalgae species. Occhipinti PS, Russo N, Foti P, Zingale IM, Pino A, Romeo FV, Randazzo CL, Caggia C. J Sci Food Agric. 2023 Nov 16.
  • Natural Compounds and Glutathione: Beyond Mere Antioxidants. Di Giacomo C, Malfa GA, Tomasello B, Bianchi S, Acquaviva R. Antioxidants (Basel). 2023 Jul 18;12(7):1445. doi: 10.3390/antiox12071445.
  • Evaluation of the Antioxidant and Antiangiogenic Activity of a Pomegranate Extract in BPH-1 Prostate Epithelial Cells. Consoli V, Burò I, Gulisano M, Castellano A, D'Amico AG, D'Agata V, Vanella L, Sorrenti V. Int J Mol Sci. 2023 Jun 27;24(13):10719. doi: 10.3390/ijms241310719
  • Standardized Extract from Wastes of Edible Flowers and Snail Mucus Ameliorate Ultraviolet B-Induced Damage in Keratinocytes. Vanella L, Consoli V, Burò I, Gulisano M, Giglio MS, Maugeri L, Petralia S, Castellano A, Sorrenti V. Int J Mol Sci. 2023 Jun 15;24(12):10185. doi: 10.3390/ijms241210185.
  • Influence of olive cake dietary supplementation on fecal microbiota of dairy cows. Russo N, Floridia V, D'Alessandro E, Lopreiato V, Pino A, Chiofalo V, Caggia C, Liotta L, Randazzo CL. Front Microbiol. 2023 May 3;14:1137452. doi: 10.3389/fmicb.2023.1137452. eCollection 2023.
  • Novel Insights on Ferroptosis Modulation as Potential Strategy for Cancer Treatment: When Nature Kills. Consoli V, Fallica AN, Sorrenti V, Pittalà V, Vanella L. Antioxid Redox Signal. 2023 Jun 28. doi: 10.1089/ars.2022.0179.
  • Wild Artichoke ( Cynara cardunculus subsp. sylvestris, Asteraceae) Leaf Extract: Phenolic Profile and Oxidative Stress Inhibitory Effects on HepG2 Cells. Acquaviva R, Malfa GA, Santangelo R, Bianchi S, Pappalardo F, Taviano MF, Miceli N, Di Giacomo C, Tomasello B. Molecules. 2023 Mar 8;28(6):2475. doi: 10.3390/molecules28062475.
  • Technological Characterization of Lactic Acid Bacteria Strains for Potential Use in Cheese Manufacture. Nicosia FD, Pino A, Maciel GLR, Sanfilippo RR, Caggia C, de Carvalho AF, Randazzo CL. Foods. 2023 Mar 9;12(6):1154. doi: 10.3390/foods12061154.
  • Effect of Astaxanthin on Tissue Transglutaminase and Cytoskeletal Protein Expression in Amyloid-Beta Stressed Olfactory Ensheathing Cells: Molecular and Delayed Luminescence Studies. Campisi A, Sposito G, Grasso R, Bisicchia J, Spatuzza M, Raciti G, Scordino A, Pellitteri R. Antioxidants (Basel). 2023 Mar 19;12(3):750. doi: 10.3390/antiox12030750.
  • Chemical Profile, Antioxidant and Cytotoxic Activity of a Phenolic-Rich Fraction from the Leaves of Brassica fruticulosa subsp. fruticulosa (Brassicaceae) Growing Wild in Sicily (Italy). Davì F, Taviano MF, Acquaviva R, Malfa GA, Cavò E, Arena P, Ragusa S, Cacciola F, El Majdoub YO, Mondello L, Miceli N. Molecules. 2023 Mar 1;28(5):2281. doi: 10.3390/molecules28052281.
  • Protective Effect of Treated Olive Mill Wastewater on Target Bacteria and Mitochondrial Voltage-Dependent Anion-Selective Channel 1. Foti P, Conti-Nibali S, Randazzo CL, Reina S, Romeo FV, Caggia C, De Pinto V. Antioxidants (Basel). 2023 Jan 30;12(2):322. doi: 10.3390/antiox12020322.
  • Colon Delivery of Nutraceutical Ingredients by Food-Grade Polymeric Systems: An Overview of Technological Characterization and Biological Evaluation. Rizzo, S.; Zingale, E.; Romeo, A.; Lombardo, R.; Pignatello, R. Appl. Sci. 2023, 13, 5443.doi.10.3390/ app13095443
  • Neurobiology and Applications of Inositol in Psychiatry: A Narrative Review. Concerto, C.; Chiarenza, C.; Di Francesco, A.; Natale, A.; Privitera, I.; Rodolico, A.; Trovato, A.; Aguglia, A.; Fisicaro, F.; Pennisi, M.; et al. Curr. Issues Mol. Biol. 2023, 45,1762–1778. doi.10.3390/cimb45020113
  • Food-grade polymers: A new vision in the controlled release of bioactive substances. S. Rizzo, E. Zingale, R. Lombardo, R. Pignatello;  Journal of Physics: Conference Series, Volume 2579 (2023), NanoInnovation 2022 19/09/2022 - 23/09/2022 Rome, Italy  
  • A microscopy evidence of the behavior of pH-sensitive food-grade polymeric delivery systems. Rizzo S, Cosentino G, Zingale E, Bonaccorso A, Petralia S, Monforte F, Condorelli GG, Carbone C, Pignatello R. Current Nutraceuticals, 4, 2023; Article ID: e010223213354;      
  • Oral Intake of the Commercial Probiotic Blend Synbio® for the Management of Vaginal Dysbiosis. Pino A, Rapisarda AMC, Vaccalluzzo A, Sanfilippo R, Coman M, Grimaldi RL, Caggia C, Randazzo C, Russo N, Panella M, Cianci A , Verdenelli MC.   J Clin Med 2022 Dec 20;12(1):27. doi: 10.3390/jcm12010027
  • Biological Investigation and Chemical Study of Brassica villosa subsp. drepanensis (Brassicaeae) Leaves. Malfa G, De Leo M, Tundis R, Braca A, Loizzo M, Di Giacomo C, Raimondo F, Bucchini A, Acquaviva R.   Molecules 2022 Dec 2;27(23):8447. doi: 10.3390/molecules27238447.
  • Lacticaseibacillus rhamnosus CA15 (DSM 33960) as a Candidate Probiotic Strain for Human Health. Pino A, Vaccalluzzo A, Caggia C, Balzaretti S, Vanella L, Sorrenti V, Ronkainen A, Satokari R, Randazzo C.   Nutrients 2022 Nov 19;14(22):4902. doi: 10.3390/nu14224902
  • Effect of Unloaded and Curcumin-Loaded Solid Lipid Nanoparticles on Tissue Transglutaminase Isoforms Expression Levels in an Experimental Model of Alzheimer's Disease. Campisi A, Sposito G, Pellitteri R, Santonocito D, Bisicchia J, Raciti G, Russo C, Nardiello P, Pignatello R, Casamenti F, Puglia C. Antioxidants (Basel) 2022 Sep 21;11(10):1863. doi: 10.3390/antiox11101863.
  • Heme Oxygenase Modulation Drives Ferroptosis in TNBC Cells. Consoli V, Sorrenti V, Pittalà V, Greish K, D'Amico AG, Romeo G, Intagliata S, Salerno L, Vanella L. Int J Mol Sci. 2022; 23(10):5709. doi: 10.3390/ijms23105709.
  • Beneficial Effects of Standardized Extracts from Wastes of Red Oranges and Olive Leaves. Burò I, Consoli V, Castellano A, Vanella L, Sorrenti V.  Antioxidants. July 2022. DOI:10.3390/antiox11081496.
  • A Systematic Review on the Effect of Nutraceuticals on Antidepressant-Induced Sexual Dysfunctions: From Basic Principles to Clinical Applications. C. Concerto, A. Rodolico, V. Meo, D. Chiappetta, M. Bonelli, L. Mineo, G. Saitta, S. Stuto, M.S. Signorelli, A. Petralia, G. Lanza, E. Aguglia. Curr. Issues Mol. Biol. 2022, 44, 3335–3350; DOI: 10.3390/cimb44080230.
  • Phytocomplex of a Standardized Extract from Red Orange (Citrus sinensis L. Osbeck) against Photoaging. Tomasello B., Malfa G.A., Acquaviva R., La Mantia A., Di Giacomo C.     Cells 2022, 11, 1447.doi.10.3390/cells11091447
  • Orobanche crenata Forssk. extract affects human breast cancer cell MCF-7 survival and viral replication. Genovese C., Garozzo A., D’Angeli F., Malfa G.A., Bellia F., Tomasello B., Nicolosi D., Malaguarnera R., Ronsisvalle S., Guadagni F., Acquaviva R.    Cells 2022, 11, 1696.doi.10.3390/cells11101696

Progetti di ricerca / Research Projects

Ultima modifica: 
03/03/2026 - 10:08